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Those who are infected may spread the disease for up to 6 weeks even if no symptoms are present. Poliovirus colonizes the gastrointestinal tract, specifically intestine and oropharynx and after about a week, it invades local lymphoid tissue and enters bloodstream,

and then may infect cells of the central nervous system. Replication of poliovirus in motor neurons of the anterior horn and brain stem results in destruction of cell and thus causes the typical manifestations of poliomyelitis. This is projected to favor a significant growth for polio vaccines market over the forecast period.

Symptoms of Poliomyelitis:

Polio mainly affects children under 5 years of age. Up to 70% of all the infections in children are without any symptoms and about 25-30% of infections in children causes’ nonspecific illness without clinical or laboratory evidence of central nervous system invasion. This has created a gesture for the organizations to focus on the vaccines options for making prophylactic approach towards the prevention of the disorder, which in turn is expected to fuel the polio vaccines market in the near future.

Polio vaccines market relies on the fact that around 1% of polio cases can develop into paralytic polio which causes paralysis in the spinal cord (spinal polio), brainstem (bulbar polio), or both (bulbospinal polio).According to WHO, 1 in 200 infections leads to irreversible paralysis. Among those paralyzed, 5% to 10% die when their breathing muscles become immobilized. The statistics regarding the prevalence of the disorder is expected to be one of the crucial factor that is to fuel the market of polio vaccines.